|
Symbol Name ID |
Bmp4
bone morphogenetic protein 4 MGI:88180 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Unroofed coronary sinus |
Atrial septal defect |
Primum atrial septal defect |
Secundum atrial septal defect |
Sinus venosus atrial septal defect |
Right ventricular dilatation |
Cardiomegaly |
Stroke |
Systolic heart murmur |
Pulmonary arterial hypertension |
Right axis deviation |
Palpitations |
Atrial fibrillation |
Atrial flutter |
Right bundle branch block |
Congestive heart failure |
| Disease(s) Associated with BMP4 | ||||||||||||||||
| atrial heart septal defect |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal artery morphology |
abnormal pharyngeal arch artery morphology |
abnormal pulmonary artery morphology |
aortopulmonary window |
abnormal aortic arch and aortic arch branch attachment |
interrupted aortic arch, type b |
abnormal retina blood vessel pattern |
abnormal angiogenesis |
abnormal vascular smooth muscle morphology |
heart right ventricle hypertrophy |
abnormal cardiac mesenchyme morphology |
abnormal cardiac outflow tract development |
abnormal conotruncal ridge morphology |
conotruncal ridge hypoplasia |
abnormal truncus arteriosus septation |
persistent truncus arteriosus |
abnormal heart development |
abnormal atrioventricular cushion morphology |
abnormal heart looping |
abnormal heart morphology |
abnormal heart and great artery attachment |
double outlet right ventricle |
common atrioventricular valve |
atrial septal defect |
ostium primum atrial septal defect |
complete atrioventricular septal defect |
partial atrioventricular septal defect |
perimembraneous ventricular septal defect |
semilunar valve hypoplasia |
pericardial effusion |
abnormal heart right ventricle pressure |
abnormal vascular endothelial cell physiology |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||
| Bmp4tm1b(EUCOMM)Hmgu/Bmp4tm1b(EUCOMM)Hmgu | ||||||||||||||||||||||||||||||||||
| Bmp4tm1Blh/Bmp4tm1Blh | ||||||||||||||||||||||||||||||||||
| Bmp4tm2(tetO-Bmp4,lacZ)Jfm/Bmp4tm2(tetO-Bmp4,lacZ)Jfm | ||||||||||||||||||||||||||||||||||
| Bmp4tm1.1Jlch/Bmp4tm2Blh | ||||||||||||||||||||||||||||||||||
| Bmp4tm1Blh/Bmp4+ | ||||||||||||||||||||||||||||||||||
| Bmp4tm1Blh/Bmp4tm3.1Blh | * | |||||||||||||||||||||||||||||||||
| Bmp4tm2Blh/Bmp4+ | ||||||||||||||||||||||||||||||||||
| Bmp4tm1Jfm/Bmp4tm1Jfm Tg(Mef2c-cre)2Blk/0 (conditional) |
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| Bmp4tm3.1Blh/Bmp4tm3.1Blh Tg(Tnnt2-cre)5Blh/0 (conditional) |
* | |||||||||||||||||||||||||||||||||
| Bmp4tm1Blh/Bmp4tm3.1Blh Tg(Tnnt2-cre)5Blh/0 (conditional) |
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| Bmp4tm1Jfm/Bmp4tm1.1Jfm Nkx2-5tm1(cre)Rjs/Nkx2-5+ (conditional) |
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| Bmp4tm1Jfm/Bmp4tm1.1Jfm Tg(Prrx1-cre)1Cjt/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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